Prof. Ying Liao | Animal virus | Best Researcher Award

Shanghai Veterinary Research Institute, Chinese Academy of Agricultutral Science | China.

Author Profile

🎓EARLY ACADEMIC PURSUITS

Prof. Ying Liao began her academic journey with a B.Sc. from East China Normal University (1993–1997), laying the groundwork for her passion in molecular virology and infectious diseases. She further honed her expertise through a Ph.D. in Biological Sciences at Nanyang Technological University, Singapore (2002–2007), where she embarked on groundbreaking research into coronavirus biology and viral-host interactions, setting the tone for a stellar scientific career.

💼PROFESSIONAL ENDEAVORS

Prof. Liao’s professional path reflects her unwavering commitment to virology research and leadership. She held research fellow positions at both Nanyang Technological University and the Institute of Molecular and Cell Biology, A*STAR Singapore, between 2007–2014. In 2014, she joined the Shanghai Veterinary Research Institute (SHVRI) of the Chinese Academy of Agricultural Sciences (CAAS) as a Professor, where she currently serves as Group Leader and Principal Investigator of the Avian Viral Diseases Team. Her team is central to China’s national strategy on animal infectious disease control and vaccine innovation.

🔬CONTRIBUTIONS AND RESEARCH FOCUS ON ANIMAL VIRUS

Prof. Ying Liao’s research centers on animal virus pathogenesis, especially coronaviruses, flaviviruses, and paramyxoviruses. Her work has made significant contributions in:

Understanding virus-host molecular mechanisms
Dissecting immune evasion pathways
Developing diagnostic tools and antiviral therapeutics
Exploring translational control during infection

Her team uses coronavirus and paramyxovirus models to study innate immunity suppression, stress granule manipulation, and translation shutoff, delivering insights that are not only academically profound but also clinically and agriculturally impactful.

🌍IMPACT AND INFLUENCE

Prof. Liao’s discoveries have broad implications in the fields of veterinary virology, pandemic preparedness, and vaccine design. Her research has informed global scientific understanding of zoonotic diseases and has contributed directly to the development of protective vaccines and antiviral strategies against infectious bronchitis virus (IBV) and Newcastle Disease Virus (NDV). As an internationally respected virologist, she continues to collaborate with leading figures across Asia, Europe, and the Americas, enhancing One Health frameworks worldwide.

🏆RESEARCH GRANTS AND FUNDING

Prof. Ying Liao has successfully led and secured over 12 major research grants, including:

🇨🇳 National Natural Science Foundation of China (NSFC)
🧬 National Key R&D Program of China
🧪 Shanghai Natural Science Foundation
🏛 Chinese Academy of Agricultural Sciences (CAAS) Elite Youth Program
🔬 Public-Interest Scientific Institution Basal Research Fund

Collectively, these projects total millions in funding, empowering extensive research into coronavirus immune evasion, host translation shutoff, stress granules, and avian vaccine development.

🦠LEGACY AND FUTURE CONTRIBUTIONS

Prof. Liao is shaping the future of infectious disease research in China and beyond. Her legacy includes:

The development of a cell line expressing furin protein for avian coronavirus culture (patented)
The training and mentorship of numerous postdoctoral researchers and graduate students
Significant strides toward universal vaccine strategies for coronaviruses
Leadership in the design of molecular diagnostic reagents for rapid outbreak response

Her dedication ensures that her work will outlive current global health challenges and serve as a foundation for next-generation viral therapeutics.

🌟A VISIONARY IN INFECTIOUS DISEASES

A trailblazer in veterinary and molecular virology, Prof. Ying Liao embodies the rare blend of scientific excellence, innovative thinking, and societal relevance. Her relentless pursuit of knowledge in host-pathogen interactions, vaccine innovation, and immune regulation has solidified her role as a visionary leader in infectious diseases. Her strategic foresight and collaborative mindset continue to transform how the scientific community responds to animal and zoonotic viral threats.

📑NOTABLE PUBLICATIONS

🧪Coronavirus endoribonuclease nsp15 suppresses host protein synthesis and evades PKR-eIF2α-mediated translation shutoff to ensure viral protein synthesis

Authors: Gong, Xiaoqian; Feng, Shanhuan; Wang, Jiehuang; Forlenza, Maria; Liao, Ying
Year: 2025
Journal: PLoS Pathogens

🧪Targeting host integrated stress response: lead discovery of flavonoid compounds active against coronaviruses PEDV and PDCoV

Authors: Yi, Liang; Wang, Yishuai; Wang, Jiehuang; Liao, Ying; Zhang, Qingwen
Year: 2024
Journal: RSC Medicinal Chemistry

🧪Newcastle disease virus infection induces parthanatos in tumor cells via calcium waves

Authors: Qu, Yang; Wang, Siyuan; Jiang, Hui; Sun, Yingjie; Ding, Chan
Year: 2024
Journal: PLoS Pathogens

🧪 Coronavirus nucleocapsid protein enhances the binding of p-PKCα to RACK1: Implications for inhibition of nucleocytoplasmic trafficking and suppression of the innate immune response

Authors: Xue, Wenxiang; Chu, Hongyan; Wang, Jiehuang; Ding, Chan; Liao, Ying
Year: 2024
Journal: PLoS Pathogens

🧪FGFR1-mediated enhancement of foot-and-mouth disease virus entry

Authors: Wang, Xuefei; Liao, Ying; Abdullah, Sahibzada Waheed; Sun, Shiqi; Guo, Huichen
Year: 2024
Journal: Veterinary Microbiologyy

China Animal Disease Control Center | China.

Author Profile

Scopus

🎓Education

Dr. Yuliang Liu, born on October 22, 1973, in Inner Mongolia, China, is a renowned professor at the China Animal Disease Control Center (CADC) since 2012. He holds a Ph.D. in Veterinary Science from Yangzhou University (2005), an M.Sc. in Veterinary Science from Guangxi University (2001), and a B.Sc. in Veterinary Medicine from Inner Mongolia Agricultural University (1998). His global experience includes postdoctoral research at the University of Pennsylvania (USA) and the Technical University of Denmark (DTU).

💼Professional Experience

Dr. Liu has over two decades of expertise in animal and zoonotic disease control, diagnostics, biosafety measures, and vaccine development. His work spans international collaborations and significant contributions to drafting Chinese standards for diagnosing animal diseases. He has supervised 17 students, including undergraduates and Ph.D. candidates, fostering future leaders in veterinary science.

🔬Technical Skills

Dr. Liu is skilled in molecular biology techniques, including reverse genetics, nucleic acid detection, and antimicrobial resistance research. His expertise in preparing Certified Reference Materials (CRMs) has led to the commercialization of five CRMs, enhancing diagnostic tools in veterinary medicine.

🔬Research Interests

A proponent of the One-Health approach, Dr. Liu focuses on animal disease surveillance, control, and vaccine innovation, emphasizing the intersection of animal and human health. His research extends to AMR studies and biosafety technologies.

📚Academic Contributions

Dr. Liu is an editor for the journal Viruses and a member of professional societies like the American Society for Virology and the Chinese Veterinary Association. As a peer reviewer, he contributes to esteemed journals, including Viruses, Gene, and JAC-Antimicrobial Resistance.

🏆Awards & Recognition

Shen Nong China Agricultural Science and Technology Award (2017, 1st Prize)
Innovation Prize of DA BEI NONG Science and Technology Award (2015)
Named Outstanding Employee of CADC (2020–2022)

🎙️Teaching & Conferences

Dr. Liu has presented research globally, including at the World Organization for Animal Health (OIE) and the American Society for Virology. His mentorship has shaped the careers of many in the veterinary field.

Through his work, Dr. Liu continues to bridge scientific innovation and practical solutions for animal health worldwide.

📑Notable Publications

“Development of Broad-Spectrum Nanobodies for the Therapy and Diagnosis of SARS-CoV-2 and Its Multiple Variants”

Authors: He, L.; Wu, Q.; Zhang, Z.; Fan, R.; Li, Y.-P.
Year: 2024
Journal: Molecular Pharmaceutics, 21(8), pp. 3866–3879

“The proteomic analysis uncovers the cellular responses to the African swine fever virus membrane proteins p54, p17, and pB117L”

Authors: Chen, Y.; Ni, J.; Wang, C.; Wei, Y.; Liu, Y.
Year: 2024
Journal: Microbes and Infection, 26(5-6), Article 105348

“Establishment of a Triplex qPCR Assay for Differentiating Highly Virulent Genotype I Recombinant Virus from Low-Virulence Genotype I and Genotype II African Swine Fever Viruses Circulating in China”

Authors: Ding, L.; Ren, T.; Bing, G.; Sun, E.; Zhao, D.
Year: 2024
Journal: Transboundary and Emerging Diseases, Article ID 6206857

“Sequence characteristics and phylogenetic analysis of H9N2 subtype avian influenza A viruses detected from poultry and the environment in China, 2018”

Authors: Gao, X.; Wang, N.; Chen, Y.; Wang, C.; Liu, Y.
Year: 2021
Journal: PeerJ, 9, Article e12512

“An oligonucleotide-tagged microarray for routine diagnostics of colon cancer by genotyping KRAS mutations”

Authors: Liu, Y.; Gudnason, H.; Li, Y.-P.; Bang, D.D.; Wolf, A.
Year: 2014
Journal: International Journal of Oncology, 45(4), pp. 1556–1564