Dr. Jialin Wang | Immunity | Best Researcher Award

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Dr. Jialin Wang | Immunity | Best Researcher Award

Central China Normal University | China.

Author Profile

Scopus

🎓EARLY ACADEMIC PURSUITS

Dr. Jialin Wang began his academic journey with a Bachelor of Science in Biology from Anhui Normal University (2000–2004), where he laid the foundational knowledge in life sciences. He further specialized by obtaining his Ph.D. in Biochemistry and Molecular Biology from Shandong University in 2009. His doctoral research ignited a lifelong focus on molecular immunology and insect biology, providing the groundwork for a highly productive scientific career.

💼PROFESSIONAL ENDEAVORS

Dr. Wang’s professional career has been rooted at the School of Life Sciences, Central China Normal University in Wuhan, China. He was appointed as an Assistant Professor (2009–2012) and later promoted to Associate Professor (2012–present). His international academic exposure includes visiting scholar positions at the University of California, Riverside (2015–2016, 2019–2020), and a stint as a Research Assistant at The University of Hong Kong (2012). These experiences expanded his expertise in insect molecular biology and comparative immunology.

🔬CONTRIBUTIONS AND RESEARCH FOCUS ON IMMUNITY

Dr. Wang has built a distinguished research portfolio centered on:

  • 🦋 Insect innate immunity

  • 🧠 Endocrine-immune system interactions

  • 🧬 Molecular regulation of immune genes by hormones such as 20-hydroxyecdysone (20E)

  • 🛡️ Pattern recognition receptors (PRRs) and cellular/humoral immune responses

His work particularly shines in elucidating the cross-talk between endocrine signals and immune defense mechanisms in model pests like Helicoverpa armigera and Spodoptera frugiperda. His studies reveal how steroid hormones modulate immune responses, offering new targets for pest control.

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🌍IMPACT AND INFLUENCE

With over 20+ high-impact publications, Dr. Wang’s findings are contributing to global understanding of insect immune biology, paving the way for:

  • 🌾 Sustainable agricultural pest management

  • 🧪 Bioengineering of immune-regulatory pathways

  • 🌐 Cross-species immunological insights relevant to infectious disease modeling

His international collaborations, notably with scientists like Dr. Alexander S. Raikhel, have placed his research within the global framework of vector-borne disease control and immunity studies.

🏆RESEARCH GRANTS AND FUNDING

Dr. Wang has successfully led and contributed to multiple competitive national and provincial projects, totaling millions in RMB funding. His grants include:

  1. 🧬 NSFC #32470517 (2025–2028): Gut immunity & metamorphosis in Helicoverpa armigera.

  2. 🔍 NSFC #31872301 (2019–2022): Hemocytic encapsulation regulated by PRPs and 20E.

  3. 💡 NSFC #31101672 (2012–2014): Immune gene identification post-20E treatment.

  4. 🌿 Hubei Foundation #2016CFB560 & 2010CDB01204: Functional analysis of C-type lectins & novel insecticide targets.

These projects emphasize his expertise in immune-endocrine dynamics and his drive to develop eco-friendly pest control solutions.

🦠LEGACY AND FUTURE CONTRIBUTIONS

Dr. Wang’s scholarly output reflects a systematic deconstruction of insect immunity at the molecular level. By pioneering studies on C-type lectins, PRRs, and hormone-immune regulation, he has built a foundation for future innovations in:

  • 🦠 Host-pathogen interaction modeling

  • 🌾 Biological pest control strategies

  • 🧪 Synthetic biology applications in immunology

He is mentoring the next generation of researchers, and his legacy is marked by a vision of biological control that respects ecological integrity.

🌟A VISIONARY IN INFECTIOUS DISEASES

By decoding the molecular choreography between hormones and immunity in insects, Dr. Wang contributes to broader insights into infectious disease resistance, vector control, and immunological adaptation. His findings may one day aid in understanding pathogen manipulation of host immune systems across species.

📑NOTABLE PUBLICATIONS

The ecdysone-induced bZIP transcription factor MafB establishes a positive feedback loop to enhance vitellogenesis and reproduction in the Aedes aegypti mosquito

Authors: Jialin Wang, Ziqian Zhong, Yazhou He, Yufeng Wang, Alexander S. Raǐkhel
Year: 2025
Journal: Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Citations: 2​

A CTL − Lys immune function maintains insect metamorphosis by preventing gut bacterial dysbiosis and limiting opportunistic infections

Authors: Pei Xiong, Wenwen Wang, Xusheng Liu, Yufeng Wang, Jialin Wang
Year: 2024
Journal: BMC Biology
Citations: 1​

An entomopathogenic fungus exploits its host humoral antibacterial immunity to minimize bacterial competition in the hemolymph

Authors: Jialin Wang, Jing Sun, Ya Jing Song, Li Li, Xusheng Liu
Year: 2023
Journal: Microbiome
Citations: 15

Prof. Zhiyi He | Immunology of Infections | Best Researcher Award

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Prof. Zhiyi He | Immunology of Infections | Best Researcher Award

The First Affiliated Hospital of Guangxi Medical University | China.

Author Profile

Scopus

🎓EARLY ACADEMIC PURSUITS

Professor Zhiyi He embarked on his academic journey with a focus on respiratory medicine, excelling during his medical training. His dedication to advancing healthcare led him to pursue rigorous education and research, establishing a strong foundation for his future endeavors.

🩺PROFESSIONAL ENDEAVORS

Position: Professor and Doctoral Supervisor at The First Affiliated Hospital of Guangxi Medical University.

Roles:

  • Member of the Respiratory Society of the Chinese Medical Association.
  • Young Member of the Chinese Respiratory Society.
  • Member of the COPD Group of the Chinese Respiratory Society.
  • Chairman of the Respiratory Disease Branch of the Guangxi Medical Association.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON IMMUNOLOGY OF INFECTIONS

Professor Zhiyi He’s research is pivotal in addressing chronic respiratory diseases, with a particular emphasis on:

  • Chronic Obstructive Pulmonary Disease (COPD).
  • Advancing diagnostic and therapeutic approaches for respiratory illnesses.
  • Promoting interdisciplinary research to integrate cutting-edge treatments.

🌍IMPACT AND INFLUENCE

Professor He’s contributions have significantly shaped respiratory medicine, not only within Guangxi but across China. As the Chairman of the Respiratory Disease Branch of the Guangxi Medical Association, he has spearheaded initiatives to improve healthcare accessibility and quality for patients with chronic respiratory conditions.

📚ACADEMIC CITATIONS

With numerous publications in high-impact journals, Professor Zhiyi He is widely cited in the fields of respiratory medicine and clinical research. His work has influenced academic peers and practitioners, reflecting his stature as a thought leader in his domain.

🦠LEGACY AND FUTURE CONTRIBUTIONS

Achievements: Named the 2020 Outstanding Scholar of Guangxi Colleges and Universities, a testament to his enduring contributions to academia and healthcare.

Vision: Professor He aims to continue driving innovation in respiratory medicine through mentorship, research, and clinical practice, leaving a lasting legacy for future generations of medical professionals.

📑NOTABLE PUBLICATIONS 

“Multiple pathogen infections accompanied with ocular pathologies in a patient with high-titer Anti-IFN-γ autoantibodies: a case report” 

Authors: Wu, S., Liang, S., Liang, H., Li, X., He, Z.
Journal: BMC Infectious Diseases
Publication Year: 2024

“Effect of high-dose N-acetylcysteine on exacerbations and lung function in patients with mild-to-moderate COPD: a double-blind, parallel group, multicentre randomised clinical trial” 

Authors: Zhou, Y., Wu, F., Shi, Z., Liu, S., Zhao, Z.
Journal: Nature Communications
Year: 2024

“Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice” 

Authors: Wang, Q., He, Z., Zhu, J., Yang, L., Yang, H.
Journal: BMC Biotechnology
Year: 2024

“Multiple intracellular pathogen infections with ocular pathologies associated with adult-onset immunodeficiency due to anti-interferon-γ autoantibodies: a case report” 

Authors: Ning, Y., Yu, Q., Liang, H., Liang, X., He, Z.
Journal: BMC Infectious Diseases
Year: 2024

“Mechanism of cigarette smoke in promoting small airway remodeling in mice via STAT 3 / PINK 1-Parkin / EMT” 

Authors: Wei, Y., Li, Q., He, K., Li, M., He, Z.
Journal: Free Radical Biology and Medicine
Year: 2024

Prof. Shu-Ching Hsu | Immunology of Infections | Best Researcher Award

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Prof. Shu-Ching Hsu | Immunology of Infections | Best Researcher Award

Prof. Shu-Ching Hsu, National Health Research Institute/National Institute of Infectious Diseases and Vaccinology, Taiwan.

Prof. Shu-Ching Hsu is an Associate Investigator at the National Institute of Infectious Diseases and Vaccinology (NIIDV), NHRI, Taiwan. She earned her Ph.D. in Molecular Immunology and Signal Transduction from National Taiwan University and specializes in immunology, stem cell biology, and vaccine development. Prof. Hsu is widely recognized for her pioneering research on immune suppression, neutrophil biology, and the development of humanized mouse models to study immune responses in infectious diseases. Her work has significantly advanced immunotherapy, drug discovery, and our understanding of immune mechanisms in disease progression. She was honored with the Best Researcher Award for her exceptional contributions to the field of immunology and infectious diseases.

Author Profile

Scopus

🏫EARLY ACADEMIC PURSUITS

Dr. Shu-Ching Hsu earned her Ph.D. in Molecular Immunology and Signal Transduction from the Graduate Institute of Microbiology, National Taiwan University (1995–2000). Prior to this, she completed her M.S. in Molecular Biology and Immunology at National Yang-Ming University (1993–1995) and her B.S. in Microbiology from Soochow University (1989–1993).

💼 PROFESSIONAL ENDEAVORS

Dr. Shu-Ching Hsu has extensive professional experience in both research and academia. She is currently an Associate Investigator at the National Institute of Infectious Diseases and Vaccinology (NIIDV), NHRI, Taiwan (2013–present) and holds Associate Professor positions at National Chung Hsing University, National Defense University, and Kaohsiung Medical University (2013–present). Prior to her current roles, she served as an Assistant Investigator at the Vaccine Research and Development Center, NHRI, Taiwan (2005–2013). Dr. Hsu also completed two postdoctoral fellowships: one at Tulane University, USA (2002–2005) and another at Academia Sinica, Taiwan (2000–2002).

🔬RESEARCH INTERESTS

Dr. Shu-Ching Hsu’s research interests focus on human neutrophil biology and progenitor cell differentiation, as well as the development of humanized mouse models for advancing immunotherapy and drug discovery. She is also deeply engaged in understanding the mechanisms of immune suppression, particularly through myeloid-derived suppressive cells (MDSCs), and their role in disease progression. Additionally, Dr. Hsu explores stem cell-based therapies aimed at addressing infectious diseases, cancer, and various immune disorders.

🧠TECHNICAL SKILLS

Dr. Shu-Ching Hsu possesses expertise in stem cell biology, particularly in the development and use of humanized mouse models for immunotherapy and drug discovery. She is proficient in neutrophil biology, cell signaling, and understanding immune suppression mechanisms. Additionally, Dr. Hsu is skilled in the genetic modification of hematopoietic stem cells (HSCs) and the creation of stem cell-derived immune cell platforms for research and therapeutic applications.

📑 NOTABLE PUBLICATIONS 

“IL-10RA governs the expression of IDO in the instruction of lymphocyte immunity” 

Authors: Tai, T.-S., Hsu, D.-W., Yang, Y.-S., Wu, C.-H., Hsu, S.-C.
Publication Year: 2024
Citations: 0

“Peptide immunization against the C-terminal of alpha-synuclein reduces locomotor activity in mice overexpressing alpha-synuclein” 

Authors: Chiu, Y.-S., Wu, K.-J., Yu, S.-J., Wang, Y., Chen, Y.-H.
Publication Year: 2023
Citations: 1

“Correction: Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells” 

Authors: Chan, T.-S., Hsu, C.-C., Pai, V.C., Weaver, V.M., Tsai, K.K.
Publication Year: 2023
Citations: 0

“The potential of adoptive transfer of γ9δ2 T cells to enhance blinatumomab’s antitumor activity against B-cell malignancy” 

Authors: Chen, Y.-H., Wang, Y., Liao, C.-H., Hsu, S.-C.
Publication Year: 2021
Citations: 4

“Index of cancer-associated fibroblasts is superior to the epithelial–mesenchymal transition score in prognosis prediction” 

Authors: Ko, Y.-C., Lai, T.-Y., Hsu, S.-C., Lin, C.-Y., Lin, S.-F.
Publication Year: 2020
Citations: 19

“Downregulation of α-Synuclein Protein Levels by an Intracellular Single-Chain Antibody” 

Authors: Chen, Y.-H., Yu, S.-J., Wu, K.-J., Hoffer, B.J., Wang, Y.
Publication Year: 2020
Citations: 7