Xiaoxiao Liu | Immunology of Infections | Excellence in Innovation

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Assoc. Prof. Dr. Xiaoxiao Liu | Immunology of Infections | Excellence in Innovation

Science & Education | Guangdong Provincial People’s Hospital| China

Xiaoxiao Liu, Ph.D., focuses on the interplay between bacteria and bacteriophages, with a particular emphasis on the regulatory mechanisms of bacterial biofilms and prophage activation. Her research addresses critical challenges in combating antibiotic-resistant infections, where biofilms serve as physical barriers that protect bacterial communities and facilitate horizontal gene transfer. Xiaoxiao Liu has systematically elucidated the signaling pathways linking environmental cues, such as low-temperature stress, to host H-NS proteins, resulting in precise prophage activation. This work has advanced the understanding of how prophages influence population-level bacterial adaptation and biofilm dynamics. She has further explored the coupling between prophage activation and biofilm formation, revealing how bacterial populations deploy sophisticated defense strategies to resist phage infection. Xiaoxiao Liu’s research also identifies strategies for enhancing the efficacy of phage therapy, demonstrating how bacterial responses to nutrient limitations, particularly nitrogen starvation, regulate key metabolic targets such as GlnA to control biofilm dispersal. Her work offers novel approaches for disrupting biofilms using targeted metabolites, including arginine, to improve phage penetration and antibacterial outcomes. Current investigations expand on the mechanisms by which bacteria employ defense systems derived from prophages to selectively neutralize diverse phages, providing insights essential for the rational design of engineered phages. By integrating molecular microbiology, biofilm physiology, and phage biology, Xiaoxiao Liu’s research contributes foundational knowledge to the development of innovative antibacterial therapies, emphasizing both fundamental and translational aspects of microbial ecology, phage-bacteria interactions, and biofilm modulation. Her studies have implications for designing more effective phage-based treatments against persistent bacterial infections and enhancing the understanding of microbial population dynamics under environmental stress. 2,901 Citations, 26 Documents, 18 h-index.

Profiles : Scopus

Featured Publications

  1. Author(s). (2026). The diagnostic value of combined detection of GBP1, IFN-γ and IL-2 in differentiating NTM from TB infection. Clinica Chimica Acta.

  2. Author(s). (2024). Control of lysogeny and antiphage defense by a prophage-encoded kinase-phosphatase module. Nature Communications. 10 citations.

Lata Deso Abo | Development of New Vaccines | Best Researcher Award

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Mr. Lata Deso Abo | Development of New Vaccines | Best Researcher Award

Lecturer and Researcher | Haramaya University, Haramaya Institute of Technology | Ethiopia

Lata Deso Abo is a Lecturer and Researcher in the Department of Chemical Engineering at Haramaya Institute of Technology, Haramaya University, Ethiopia. He earned his Bachelor of Science degree in Chemical Engineering/Process Engineering from Haramaya University in 2017, followed by a Master of Science in Chemical Engineering with a specialization in Bioenergy Engineering from Addis Ababa Science and Technology University in 2021. His research focuses on sustainable technologies, bioenergy, waste valorization, green innovations, and advanced water treatment, with a particular emphasis on bioethanol production, biomass utilization, and the mitigation of industrial fouling in heat transfer systems. Lata has published extensively in reputable journals including Thermal Science Engineering Progress, Environmental Quality Management, Fuel, Chemosphere, and Results in Engineering, contributing studies on heat exchanger fouling, bioethanol optimization through artificial neural networks, biowaste valorization, and the development of eco-friendly biopesticides. His work has also been presented at international conferences such as EPACT-2022 and the AIP Conference Proceedings. In recognition of his scholarly contributions, he has received multiple awards and certificates for teaching performance, research excellence, and editorial reviewing roles in journals like Results in Engineering, Biomass and Bioenergy, and Journal of Environmental Management. Proficient in English and Amharic, and skilled in computational and chemical engineering tools including Aspen Plus, SuperPro Designer, MATLAB, CHEMCAD, and R programming, Lata Deso Abo combines research, teaching, and innovation to advance chemical engineering knowledge and sustainable solutions, making him a distinguished contributor to both academia and applied engineering research. He has 38 citations from 2 documents with an h-index of 2.

Profiles: Google Scholar | Scopus | ORCID

Publications

1. Chozhavendhan, S., Karthigadevi, G., Bharathiraja, B., Kumar, R. P., Abo, L. D., … (2023). Current and prognostic overview on the strategic exploitation of anaerobic digestion and digestate.

2. Jayakumar, M., Hamda, A. S., Abo, L. D., Daba, B. J., Prabhu, S. V., Rangaraju, M., … (2023). Comprehensive review on lignocellulosic biomass derived biochar production, characterization, utilization and applications.

3. Jayakumar, M., Gebeyehu, K. B., Abo, L. D., Tadesse, A. W., Vivekanandan, B., … (2023). A comprehensive outlook on topical processing methods for biofuel production and its thermal applications.

4. Areti, H. A., Muleta, M. D., Abo, L. D., Hamda, A. S., Adugna, A. A., Edae, I. T., Daba, B. J., … (2024). Innovative uses of agricultural by-products in the food and beverage sector.

5. Gari, M. T., Asfaw, B. T., Arumugasamy, S. K., Abo, L. D., … (Year). Natural resources-based activated carbon synthesis.