Prof. Ying Liao | Animal virus | Best Researcher Award
Shanghai Veterinary Research Institute, Chinese Academy of Agricultutral Science | China.
Author Profile
🎓EARLY ACADEMIC PURSUITS
Prof. Ying Liao began her academic journey with a B.Sc. from East China Normal University (1993–1997), laying the groundwork for her passion in molecular virology and infectious diseases. She further honed her expertise through a Ph.D. in Biological Sciences at Nanyang Technological University, Singapore (2002–2007), where she embarked on groundbreaking research into coronavirus biology and viral-host interactions, setting the tone for a stellar scientific career.
💼PROFESSIONAL ENDEAVORS
Prof. Liao’s professional path reflects her unwavering commitment to virology research and leadership. She held research fellow positions at both Nanyang Technological University and the Institute of Molecular and Cell Biology, A*STAR Singapore, between 2007–2014. In 2014, she joined the Shanghai Veterinary Research Institute (SHVRI) of the Chinese Academy of Agricultural Sciences (CAAS) as a Professor, where she currently serves as Group Leader and Principal Investigator of the Avian Viral Diseases Team. Her team is central to China’s national strategy on animal infectious disease control and vaccine innovation.
🔬CONTRIBUTIONS AND RESEARCH FOCUS ON ANIMAL VIRUS
Prof. Ying Liao’s research centers on animal virus pathogenesis, especially coronaviruses, flaviviruses, and paramyxoviruses. Her work has made significant contributions in:
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Understanding virus-host molecular mechanisms
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Dissecting immune evasion pathways
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Developing diagnostic tools and antiviral therapeutics
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Exploring translational control during infection
Her team uses coronavirus and paramyxovirus models to study innate immunity suppression, stress granule manipulation, and translation shutoff, delivering insights that are not only academically profound but also clinically and agriculturally impactful.
🌍IMPACT AND INFLUENCE
Prof. Liao’s discoveries have broad implications in the fields of veterinary virology, pandemic preparedness, and vaccine design. Her research has informed global scientific understanding of zoonotic diseases and has contributed directly to the development of protective vaccines and antiviral strategies against infectious bronchitis virus (IBV) and Newcastle Disease Virus (NDV). As an internationally respected virologist, she continues to collaborate with leading figures across Asia, Europe, and the Americas, enhancing One Health frameworks worldwide.
🏆RESEARCH GRANTS AND FUNDING
Prof. Ying Liao has successfully led and secured over 12 major research grants, including:
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🇨🇳 National Natural Science Foundation of China (NSFC)
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🧬 National Key R&D Program of China
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🧪 Shanghai Natural Science Foundation
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🏛 Chinese Academy of Agricultural Sciences (CAAS) Elite Youth Program
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🔬 Public-Interest Scientific Institution Basal Research Fund
Collectively, these projects total millions in funding, empowering extensive research into coronavirus immune evasion, host translation shutoff, stress granules, and avian vaccine development.
🦠LEGACY AND FUTURE CONTRIBUTIONS
Prof. Liao is shaping the future of infectious disease research in China and beyond. Her legacy includes:
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The development of a cell line expressing furin protein for avian coronavirus culture (patented)
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The training and mentorship of numerous postdoctoral researchers and graduate students
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Significant strides toward universal vaccine strategies for coronaviruses
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Leadership in the design of molecular diagnostic reagents for rapid outbreak response
Her dedication ensures that her work will outlive current global health challenges and serve as a foundation for next-generation viral therapeutics.
🌟A VISIONARY IN INFECTIOUS DISEASES
A trailblazer in veterinary and molecular virology, Prof. Ying Liao embodies the rare blend of scientific excellence, innovative thinking, and societal relevance. Her relentless pursuit of knowledge in host-pathogen interactions, vaccine innovation, and immune regulation has solidified her role as a visionary leader in infectious diseases. Her strategic foresight and collaborative mindset continue to transform how the scientific community responds to animal and zoonotic viral threats.
📑NOTABLE PUBLICATIONS
🧪Coronavirus endoribonuclease nsp15 suppresses host protein synthesis and evades PKR-eIF2α-mediated translation shutoff to ensure viral protein synthesis
Authors: Gong, Xiaoqian; Feng, Shanhuan; Wang, Jiehuang; Forlenza, Maria; Liao, Ying
Year: 2025
Journal: PLoS Pathogens
🧪Targeting host integrated stress response: lead discovery of flavonoid compounds active against coronaviruses PEDV and PDCoV
Authors: Yi, Liang; Wang, Yishuai; Wang, Jiehuang; Liao, Ying; Zhang, Qingwen
Year: 2024
Journal: RSC Medicinal Chemistry
🧪Newcastle disease virus infection induces parthanatos in tumor cells via calcium waves
Authors: Qu, Yang; Wang, Siyuan; Jiang, Hui; Sun, Yingjie; Ding, Chan
Year: 2024
Journal: PLoS Pathogens
🧪 Coronavirus nucleocapsid protein enhances the binding of p-PKCα to RACK1: Implications for inhibition of nucleocytoplasmic trafficking and suppression of the innate immune response
Authors: Xue, Wenxiang; Chu, Hongyan; Wang, Jiehuang; Ding, Chan; Liao, Ying
Year: 2024
Journal: PLoS Pathogens
🧪FGFR1-mediated enhancement of foot-and-mouth disease virus entry
Authors: Wang, Xuefei; Liao, Ying; Abdullah, Sahibzada Waheed; Sun, Shiqi; Guo, Huichen
Year: 2024
Journal: Veterinary Microbiologyy