Karine Gloux | Virulence | Best Researcher Award

Karine Gloux | Virulence | Best Researcher Award

Mrs. Karine Gloux,Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, France.

Mrs. Karine Gloux is a renowned researcher in microbiology, specializing in microbial virulence and host-pathogen interactions. Her groundbreaking work has advanced understanding of pathogen mechanisms, immune evasion, and infection establishment. With high-impact publications and prestigious awards, Gloux’s contributions influence academic and clinical approaches to infectious disease management. Her commitment to research excellence and mentoring the next generation of scientists marks her as a leading figure in global microbiological research.

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Education

Mrs. Karine Gloux holds an impressive educational background in microbiology and plant sciences. She earned her PhD in 1990 from Dr. Le Rudulier’s laboratory, where she focused on the microbiology and physiology of plant symbiosis at the University of Rennes I, France. In 1995, she completed her Diplôme d’Études Approfondies in Plant Biology and Agroalimentary at the University of Nantes, France. Prior to that, in 1994, she obtained her Master’s degree in Biochemistry from the University of Rennes I. This strong academic foundation has been integral to her pioneering research career.

Professional Experience

Mrs. Karine Gloux has held a series of esteemed positions throughout her career, contributing extensively to the field of microbiology. From 2011 to 2018, she served as a Senior Engineer/Researcher at the MICALIS institute (Microbiology of Food for Health, Université Paris-Saclay, AgroParisTech) at INRAE (National Research Institute for Agriculture, Food and the Environment) in Dr. Philippe Gaudu’s lab, where her research focused on the role of host lipids in the adaptation of Staphylococcus aureus. Prior to that, between 1998 and 2010, she worked as an Engineer at INRA, leading projects on the functional screening of metagenomics clones from human intestinal microbiota and studying the impact of food on detoxication enzymes in the human intestine and liver. Her earlier experience from 1991 to 1998 includes work in Dr. Bernard Jouan’s lab at INRA’s Plant Pathology department in Rennes, France, where she investigated the relationship between osmoregulation and virulence of Erwinia chrysanthemi on potatoes and explored genetic determinants of the cauliflower mosaic virus. Gloux also completed a post-doctoral fellowship in Dr. C. Blanc’s lab on bacterial genetics and physiology at CNRS, Rennes, from 1990 to 1991. In terms of mentorship, between 1991 and 2018, she co-supervised 1 postdoctoral fellow, 4 PhD students, 8 Master’s students, and 8 engineering students at INRAE, Rennes, and Jouy en Josas. Additionally, she has a background in academia, having been a temporary teacher and contractual assistant professor at University Rennes from 1987 to 1990.

Research Expertise

Mrs. Karine Gloux’s research expertise spans a diverse range of areas in microbiology, including bacterial physiology and bacterial stress responses, where she has contributed significantly to understanding how bacteria adapt and survive under challenging conditions. Her work in functional metagenomics has provided insights into the genetic potential of microbial communities, while her proficiency in bioinformatics has enabled the analysis and interpretation of complex biological data. Additionally, Gloux’s knowledge in lipid biochemistry has been integral to her research on host-pathogen interactions and the role of lipids in bacterial adaptation.

Top Note Publications

Title: The double-edged role of FASII regulator FabT in Streptococcus pyogenes infection

Authors: Lambert, C., Gaillard, M., Wongdontree, P., … Gruss, A., Fouet, A.
Year: 2024
Citations: 0

Title: Aquatic environment drives the emergence of cell wall-deficient dormant forms in Listeria

Authors: Carvalho, F., Carreaux, A., Sartori-Rupp, A., … Bierne, H., Pagliuso, A.
Year: 2024
Citations: 0

Title: Oxidative stress is intrinsic to staphylococcal adaptation to fatty acid synthesis antibiotics

Authors: Wongdontree, P., Millan-Oropeza, A., Upfold, J., … Anba-Mondoloni, J., Gruss, A.
Year: 2024
Citations: 0

Title: Acyl-AcpB, a FabT corepressor in Streptococcus pyogenes

Authors: Lambert, C., d’Orfani, A., Gaillard, M., … Poyart, C., Fouet, A.
Year: 2023
Citations: 2

Title: A Streptococcus pyogenes DegV protein regulates the membrane lipid content and limits the formation of extracellular vesicles

Authors: Lambert, C., Poullion, T., Zhang, Q., … Poyart, C., Fouet, A.
Year: 2023
Citations: 2

Title: Mechanisms of acetoin toxicity and adaptive responses in an acetoin-producing species, Lactococcus lactis

Authors: Cesselin, B., Henry, C., Gruss, A., Gloux, K., Gaudu, P.
Year: 2021
Citations: 14

Title: Permissive Fatty Acid Incorporation Promotes Staphylococcal Adaptation to FASII Antibiotics in Host Environments

Authors: Kénanian, G., Morvan, C., Weckel, A., Gloux, K., Gruss, A., et al.
Year: 2019
Citations: 25